The action will begin Friday at noon and will go if necessary to Monday. Seven games are possible this weekend, and for those who may be green to the NCAA Baseball Tournament, it is a double-elimination tournament.
Here are the four teams participating in this regional: Click the teams for in-depth previews.
#1 Oklahoma State (45-16), First Game: Binghamton, 7 p.m. ET ESPN3
#2 Nebraska (40-19), First Game: Cal-State Fullerton, 1 p.m. ET ESPNU
#3 California State-Fullerton (32-22), First Game: Nebraska, 1 p.m ET ESPNU
#4 Binghamton (25-25), First Game: Oklahoma State, 7 p.m. ET ESPN3